Abstract Hypoxia-inducible factors (HIFs) are broadly expressed in human cancers, and HIF1 and HIF2 were previously suspected to promote tumour progression through largely overlapping functions
Spray, swish and swallow
Retrospective evaluation of low long-term efficacy of antiepileptic drugs and ketogenic diet in 39 patients with CDKL5-related epilepsy
Depressive symptoms and social demographic, stress and health risk behaviour among university students in 26 low-, middle- and high-income countries
Cardiovascular and Renal Research Emerging research applications in cardiovascular and kidney systems: Cardiovascular Research: Blood Pressure Regulation: Investigation of systemic blood pressure effects and mechanisms Cardiac Function: Research on cardiac contractility, heart rate, and cardiac output Endothelial Function: Studies on vascular endothelial cell health and nitric oxide production Atherosclerosis Research: Investigation of plaque formation, inflammation, and lipid accumulation Cardioprotection Studies: Research on myocardial protection mechanisms in injury models Arrhythmia Research: Investigation of cardiac electrical properties and arrhythmia susceptibility Renal Function Research: Sodium Excretion: Investigation of natriuretic effects and sodium balance Glomerular Function: Research on glomerular filtration rate and kidney function markers Albuminuria Studies: Investigation of kidney injury markers and proteinuria Renal Protection: Research on diabetic nephropathy and kidney injury protection mechanisms Fluid Balance: Studies on water retention, plasma volume, and fluid homeostasis Lipid Metabolism Research: Plasma Lipids: Investigation of triglycerides, total cholesterol, LDL-C, HDL-C changes Hepatic Lipid: Research on liver triglyceride content and steatosis Adipose Lipolysis: Studies on fat mobilization and free fatty acid release Lipid Oxidation: Investigation of fatty acid oxidation in liver, muscle, and other tissues Laboratory protocols include blood pressure telemetry, echocardiography, vascular reactivity studies, plasma and tissue lipid analysis, and comprehensive metabolic profiling
