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Food Bioscience, 53 , 102698

doi: 10.1186/s13019-015-0298-6 170 NguyenBLuongLNaaseHVivesMJakajGFinchJet al

During the catalytic process, the level of cellular lipid peroxides directly affects the activity of enzymes, including cyclooxygenases (COXs) and LOXs

This reaction catalyzes the generation of ROS, further promoting lipid peroxidation and leading to lipid peroxide accumulation, ultimately inducing ferroptosis (57) (Fig

Without specific biomarkers, it is difficult to evaluate the therapeutic effects of ferroptosis-targeting agents in clinical trials and adjust treatment plans accordingly