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Furthermore, for specific compounds, additional key mechanisms such as Fas-mediated signal transduction, loss of cellular redox homeostasis, ATP depletion, changes in ion channels, and activation of kinases and caspases, among others, have been highlighted

[CrossRef] [Google Scholar] Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices

Other important constituents also include several isoflavonoid derivatives such as shinpterocarpin, glabrone, glabridin, galbrene, lico-isoflavones A and B (Asl and Hosseinzadeh, Figure 9 Due to their antioxidative properties, several species of Glycyrrhiza were investigated for possible therapeutic effects as neuroprotectants against neurodegenerative disorders such as PD, AD, and dementia

Yet, it suggests that the lncRNA SAT1 is crucial for the induction of senescence upon SAL treatment

[0339] The compound of Formula la at 100 mg/mL in water with 0.1% w/v HPMC, 0.5% w/v poloxamer 237, and 0.9% sodium chloride: The suspension vehicle containing the excipients HPMC, poloxamer 237, and sodium chloride was prepared as described above in Example 3