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Efficacy of Cathelicidin LL-37 in an MRSA Wound Infection Mouse Model

In preclinical work, Dihexa promoted dendritic spine formation at concentrations reported to be far more potent than BDNF on a molar basis in specific assays [McCoy et al., 2013]

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Mechanistically, Epitalons effect appears to involve a direct interaction with promoter regions of the telomerase gene, where it binds specific DNA sequences (such as ATTTC motifs), potentially modulating transcriptional activity