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PMID:30895708

Grant GA

Since 1948, the most used method to assay lipoperoxidation end products is based on the studies of Bernheim et al., consisting in MDA condensation with the thiobarbituric acid (TBA) leading to a red complex which can be quantified by visible absorption spectrophotometry (in the range 500-600 nm, depending on the procedure used) or fluorescence spectroscopy (Figure 5)

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Knockout mice that lack a subunit of glutamate cysteine ligase have demonstrated a significant reduction of GSH in the anterior cingulate cortex (65), which has resulted in schizophrenia-like behaviour, including hyperlocomotion and altered social behaviour (66)