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In endomyocardial biopsies, higher burdens of mtDNA mutations are associated with reduced ejection fraction and worse outcomes ( 3.3 Oxidative stress and calcium overload Oxidative stress and calcium overload are tightly interconnected mechanisms of mitochondrial dysfunction in HF

Quality control included size distribution analysis (Agilent 5400 Bioanalyzer

The activity of the Gardos channel is reduced with ageing (Tiffert et al., 2007)

Restoring GHK-Cu through injectable therapy is a powerful intervention with effects that go far beyond topical skincare

Pardo A, Ruiz V, Arreola JL, Ramrez R, Cisneros-Lira J, Gaxiola M, et al