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BPC 157 10 g/kg, intraperitoneally or per-orally, was given with l-NAME (5 mg/kg intraperitoneally) and/or L-arginine (100 mg/kg intraperitoneally) and it maintained its original beneficial effect

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Additionally, research has explored NAD+'s role in acute neurological injuries such as stroke and traumatic brain injury using experimental models, with studies suggesting that rapid NAD+ depletion following brain injury contributes to neuronal death and that NAD+ restoration may be neuroprotective in research models