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Epigenetic regulation of hematopoietic differentiation by Gfi-1 and Gfi-1b is mediated by the cofactors CoREST and LSD1

2241-A PREVALENCE OF HEPATIC STEATOSIS IN A MEXICAN THIRD LEVEL HOSPITAL AND RISK FACTORS FOR DEVELOPMENT OF CIRRHOSIS Jos Alonso vila Rojo 1 , Esmeralda Avila Rojo 1 , David Aguirre-Villarreal 2 , Ernesto Elizondo Zepeda 1 and Ignacio Garca Jurez 3 , (1)Instituto Nacional De Ciencias Mdicas y Nutricin Salvador Zubirn, (2)Instituto Nacional de Ciencias Medicas y Nutricion, (3)Instituto Nacional De Ciencias Medicas y Nutricion Background: Non-alcoholic fatty liver disease (NAFLD) has become a growing concern worldwide, with hepatic steatosis being a key component of its pathogenesis

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Therapeutically, targeting ferroptosis focuses on damaging cell membrane lipids, while targeting cuproptosis centers on inducing mitochondrial proteotoxicity