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Additionally, the use of a neutralizing anti-NGF antibody diminished GSH levels and downregulated trx-1 mRNA levels in the liver (Valdovinos-Flores and Gonsebatt, 2013)

CKD patients should consume more foods rich in dietary fiber [133, 134] and avoid high-choline foods such as L-carnitine [135] and phosphatidylcholine [136] because trimethylamine-N-oxide, generated from choline metabolism by the gut microbiota, contributes to the progression of CKD and the risk of death [137]

In view of the fact that ascorbic acid and GSH both occur in cells at similar concentrations in the low millimolar range [81], ascorbylation could have biological relevance

Vitamin C contributes to normal functioning of the nervous system

More recent studies have identified a correlation between free zinc levels and the strength of antibody responses, including the potency of neutralizing antibodies [388]