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Ghattamaneni NK, Sharma A, Panchal SK, Brown L

10.1093/toxres/tfaf024 125 XiaoM.GuoZ.YangY.HuC.ChengQ.ZhangC.et al (2024)

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PM2.5 suspended in the air can adsorb microorganisms and directly enter alveoli, markedly downregulating the activity of the anti-inflammatory factor miR-362-3p in alveolar epithelial cells and promoting the overexpression of the downstream target runt-related transcription factor 1 (RUNX1) of miR-362-3p, in which RUNX1 induces the transdifferentiation of fibroblasts into myofibroblasts, driving the occurrence of respiratory diseases, such as PF (107,108)

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