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Nature Communications, 13(1), December 2022

Like many other pathological conditions that involve deregulated covalent modifications (e.g., phosphorylation or acetylation), altered S-glutathionylation patterns have been linked to various disease states including obesity, diabetes mellitus, cardiovascular disease, inflammation, cancer, and aging (Cooper et al., 2013

Effects of combined UDP-glucuronosyltransferase (UGT) 1A1*28 and 1A6*2 on paracetamol pharmacokinetics in beta-thalassemia/HbE

Adv Colloid Interface Sci

This phenomenon has been demonstrated across multiple ovarian cancer models, with findings from both in vitro and in vivo studies supporting the role of OV-EVs in immune modulation