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These free radicals cause tissue damage by disrupting normal antioxidant defense systems and lead to cell death 44,64

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FIGURE 1 Fundoscopy We demonstrated the specific damaging effect of L-NAME application

Pro-brain natriuretic peptide (NPPB), a negative regulator of blood pressure that increases in response to heart damage, and troponin T (TNNT2), a heart muscle protein involved in contraction, had the strongest weights in the heart aging model (Fig

Acute Intermittent Porphyria: Symptoms and Triggers Acute Intermittent Porphyria (AIP) can cause sudden, severe symptoms