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Per kg dosage in mice does not scale to humans

AOD9604 is not FDAapproved for any medical indication, and FDA advisory documents note concerns about immunogenicity, peptide-related impurities, and lack of sufficient safety and efficacy data

And emerging research suggests GIP may have protective effects on brain function and bone density, areas where pure GLP-1 agonists have raised some concerns

Key finding: AOD 9604 reduced cartilage damage score by 67%, decreased MMP-13 activity by 58%, and preserved joint space width