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Abbreviations CKD chronic kidney disease CMAH cytidine monophospho- N -acetylneuraminic acid hydroxylase CVD cardiovascular disease FMO3 flavin monooxygenase 3 GM3 monosialodihexosylganglioside HCAs heterocyclic amines Neu5Ac N -acetylneuraminic acid Neu5Gc N -glycolylneuraminic acid NOCs N-nitroso compounds PAHs polycyclic aromatic hydrocarbons TGF- transforming growth factor beta TMA trimethylamine TMAO trimethylamineN-oxide WHO-IARC World Health Organization-International Agency for Research on Cancer Footnotes Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication

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Traditionally, ashwagandha has been used to support energy, enhance resilience, improve overall health, and as one of the best nootropics ingredients

Cell studies suggest that it can help maintain healthy neuron growth

10.1007/s00394-009-0003-4 97 MaG.PanB.ChenY.GuoC.ZhaoM.ZhengL.et al (2017)