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Thus, the peak concentrations after intermittent doses at steady state will be equal to the peak concentration after the first dose multiplied by the accumulation factor

In the NEJM Phase 2 trial, participants assigned to an initial dose of 4 mg experienced significantly more adverse events than those who started at 2 mg, even when both groups ultimately reached the same target dose

Cautions & Warnings: Keep out of reach of children As with all dietary supplements, consult your healthcare professional before use See product label for more information Do not use if safety seal is broken or missing Keep out of reach of children Keep your licensed health care practitioner informed when using this product

The breadth of data was presented during a late-breaking symposium at the 2026 Scientific Sessions of the American Diabetes Association (ADA) in New Orleans, June 58, alongside the simultaneous publication of REIMAGINE 1 and 2 trial results in The Lancet Diabetes & Endocrinology and the REIMAGINE 3 trial results in The Lancet