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In vivo administration of glutathiones and LPS Rats were anesthetized using intraperitoneal injection of 8 mg/kg xylazine (Bayer Yakuhin, Osaka, Japan) and 80 mg/kg ketamine (Daiichi Sankyo, Tokyo Japan)

Hum Toxicol 5:179182 Foot CL, Fraser JF, Mullany DV (2005) Pyroglutamic acidosis in a renal transplant patient

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Consequently, NRF2 dissociates from Keap1, escapes ubiquitination and degradation, accumulates in the cytoplasm, and ultimately translocates to the nucleus [85, 91, 92]

Biochem J 474:877883 Foyer CH, Souriau N, Perret S, Lelandais M, Kunert KJ, Pruvost C, Jouanin L (1995) Overexpression of glutathione reductase but not glutathione synthetase leads to increases in antioxidant capacity and resistance to photoinhibition in poplar trees