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47 Evaluation for Systemic Manifestations Once a DM diagnosis is made, it is critical to assess and follow patients for presence/development of visceral organ involvement and malignancy, as these contribute greatly to morbidity and mortality

Both genetic and non-genetic forms of DCM share pathways with hypertrophic cardiomyopathy, particularly in terms of mechanisms leading to ferroptosis (136)

Cytokine storm induced by pulmonary SARS-CoV-2 infection or intestinal impairment caused by direct gut infection could promote systematic or intestinal inflammation and contribute to gut microbiota dysbiosis (Merad and Martin, 2020

doi: 10.1055/a-1345-0173 135 AritaMBianchiniFAlibertiJSherAChiangNHongSet al

This dysregulation results in changes to the hormones that they secrete and causes conditions such as leptin resistance