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1,2,3 Recent studies further confirm that cellular senescence is a defined hallmark of organismal aging, and its accumulation plays a crucial role in aging progression

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Nanoparticles have also been developed to improve wound healing, mainly via ROS scavenging, anti-inflammatory and antibacterial effects, and applied to several in vitro and in vivo models 180,181,182,183,184 , as well as other molecules 185,186,187,188

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Importantly, daidzein has been identified as a potent inhibitor that dramatically inhibited ALOX15 activity and held promise for developing natural medicines of cardioprotection [18]