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Virgolini and Aschner 2021)

Ulas, J

An index reaction to 1 antimicrobial sulfonamide agent precludes future use of other antimicrobial sulfonamides due to interclass cross-reactivity of the shared arylamine groups allergenic determinant

In fact, the downward tilting of the TM over the area of OHC is more pronounced compared with the downward tilting of the TM over the area of IHC, which opens the RL-TM gap medially over IHC and leads a radial endolymph dragging towards the modiolus, which inhibits both OHC and IHC (see cartoons in Figure 11)