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Coppola N, Cantile T, Adamo D, et al

[38] [36] Isovaleryl-CoA is subsequently metabolized by isovaleryl-CoA dehydrogenase and converted to MC-CoA, which is used in the synthesis of acetyl-CoA and other compounds

Next, PKC inhibition abolished VEGF upregulation of A-disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1) to promote endothelial proliferation and angiogenesis in a mouse model of ischemia-induced retinal neovascularization (117)