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We cannot completely rule out the effect of recreational substances on the observed results (see Supplementary)

[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Hothorn M., Wachter A., Gromes R., Stuwe T., Rausch T., Scheffzek K

Although FDA does not currently clear or approve laboratory-developed tests in the U.S., certification of the laboratory is required under CLIA to ensure the quality and validity of the tests

X-ray crystallographic studies have demonstrated that copper coordination occurs through the N-terminal amino group of glycine, the deprotonated peptide nitrogen of the Gly-His bond, and the imidazole nitrogen of histidine, forming a square-planar geometry characteristic of Cu(II) complexes

It is a vital cofactor of numerous important enzymes, such as dopamine monooxygenase, cytochrome oxidase, and the free radical scavenger superoxide dismutase (Uauy et al., 1998