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Furthermore, it is found that the protein expression of SLC7A11 and GPX4 was downregulated in the DE and DMSO pretreated mice, and AST effectively increased both molecules, as demonstrated by Western blot and immunofluorescence staining (Figures 9D, E

This, in turn, would drive oxidatively induced cell death and increase barrier dysfunction and T2 inflammation, potentially identifying a mechanism by which viruses cause asthma exacerbations

The Journal of Nutrition, 134(3), 489-492

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