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PloS One (2017) 12(2):e0170886

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How Does Glutathione Support Detoxification

DNA damage repair fails when PARP-1 is cleaved, as the cleaved form of PARP-1 can no longer repair DNA (104106)

Results GSH prevented long-term oscillating glucose (LOsG) intake-induced prediabetes in rats To mimic human food-intake habits in rodents, we orally (by gavage) gave female rats who were having regular rat chaw an extra 6 g/kg of d-glucose every 6 h per day for 38 days (P38), which resulted in an extra 1.6 times of sugar than what they usually have