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doi:10.1021/ja508394x

wherein A100 is substituted with either a C, D, E, F, G, H, I, K, L, M, N, P, Q, R, S, T, V, W, or Y

It often modifies the function of the genes and affecting gene expression

Another possible strategy to delay aging is to express a lysosome-targeted transmembrane proton-motive force-driven transhydrogenase, such as a mammalian NNT homolog, with the nucleotide binding domain facing the cytoplasm (Figure 3B)

Latiglutenase, KumaMax, and modified subtilisins modified by PEG and in combination with PLGA microencapsulation are more recent developments that may yield formulations that can be used as to reduce and abolish immunogenicity if ingested gluten for the management of CeD