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The increased amount of GABA then downregulates the GABA receptors, making the net effect less of an inhibitory signal.[ref] GABA can also be metabolized into creatine, and an increase in both GABA and creatine is found in people with dysfunction in the ALDH5A1 gene

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Microbiologyopen 7(6):e00612 Zhou Y, Wang J, Zhao Y, Zhao Y, Yang J, Wang K, Liu X, Qu W, Zhang L, Gu X (2024) Salidroside inhibits alpha-Amanitin-induced AML-12 cell apoptosis via the regulation of PINK1/Parkin-mediated mitophagy and mitochondrial function

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In fact, hemolysis is often caused by a lack of active glutathione