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10.1016/j.intimp.2008.03.003 178 ZhaoQ.BaiJ.ChenY.LiuX.ZhaoS.LingG.et al (2022)

CB2 receptors are more prevalent in the immune system and peripheral nervous system than in the CNS, where they play pivotal role in the control of inflammation and pain ( Tetrahydrocannabinolic acid (THCa) and cannabidiolic acid (CBDa), present in plant during its growth, are converted to THC and CBD by heating process known as decarboxylation ( Cannabis sativa L