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Nevertheless, preliminary estimates can be derived based on the studies currently available

All the parameters were abnormal, with very high levels of CRP and PCT (as acute markers of inflammation and infection), while the markers for renal and hepatic insufficiency, as well as metabolic acidemia, were also very high

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For instance, the relative levels of sphingosine 1-phosphate, phytosphingosine, sphinganine 1-phosphate, and 17a-estradiol were greatly decreased, whereas those of methyl jasmonate were distinctly increased in MS-affected patients compared with healthy subjects