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Alternatively, by leveraging the sequence similarity within GST subfamilies, RNA interference targeting entire GST classes could be employed to investigate their roles in ITC detoxification

Studies have shown that increased GPx [126, 127] and catalase [128,129,130] activity improve cardiac electromechanical function and reduce ROS toxicity in animal models that have undergone IR injury, doxorubicin-induced cardiomyopathy, diabetes, and heart failure

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It can increase the expression and function of tight junction proteins, such as occludin, claudins, and zonula occludens-1 (ZO-1), which are vital components of the gut barrier (105)