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Affected peoples quality of life may be severely impacted if the condition is left untreated because it can result in long-lasting health problems like Lyme arthritis and neuroborreliosis

Clinical significance was derived from ClinVar when available

About one-half of the hepatic bile output enters the gallbladder, where it is then concentrated by a factor of 46 by removal of water and electrolytes

While the overall symptoms of AIH are similar across regions, notable differences exist in clinical presentation at diagnosis [4, 5, 9, 13,14,15, 30,31,32,33]

It also contributes to the production of glutathione, an antioxidant that helps protect cells from oxidative damage