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Key differential amino acid metabolites, such as Ala, Ile, Leu, Asp, Cys, Glu, and Gly, may play significant roles in the pathophysiology of UA

EA can increase the abundance of beneficial bacteria (such as Roseburia , Ruminococcus UCG-014 , Ruminococcus UCG-013 and Bacteroides ), and downregulate harmful bacteria such as escherichiacoli, e.coli and Klebsiella (Tan et al., 2023)