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A variety of Parkinsons disease animal models, ranging from toxin-induced to genetically modified mice, exhibit abnormalities in the operation of different ion channels ( In the field of ion channel drug discovery, a significant challenge is preventing side effects arising from both target and off-target mechanisms

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Analysis of DNA methylation associates the cystine-glutamate antiporter SLC7A11 with risk of Parkinsons disease

10.1016/j.addr.2015.10.019 98 KhalfA.MadihallyS

Therefore, patients with suspected AIH not reaching a diagnostic score result with the simplified scoring system, should be reassessed using the revised scoring system [71]