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However, over the years, large-scale clinical trials proved only limited health benefits of taking antioxidants (Halliwell 2022)

10.1038/leu.2015.157 Leukemia 31 JiaJ.BissaB.BrechtL.AllersL.ChoiS

GSH levels influenced by erastin

Similar to this, withaferin A and withanolide D inhibited the breakdown of IB and promoted the production of the antioxidant enzyme HO-1 to prevent the angiogenic activity of endothelial cells [193]