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In conclusion, IL-8 as a CXC chemokine produced by various cell types is well-known as a potent angiogenic factor through paracrine and autocrine routes in tumorigenesis

Zhang YN, Pang YX, Liu DW, Hu HJ, Xie RQ, Cui W

doi: 10.1016/S0140-6736(00)02169-3 116 El AsmarRPaningrahiPBamfordPBertiINotTCatassiCet al