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The first CD38-targeting antibody to be approved yielded strong trial results, significantly improving survival rates and earning widespread patient acceptance

GADD45 activates AMPK to enhance fatty acid oxidation and energy expenditure while suppressing lipogenesis, protecting against acetaminophen- and diet-induced liver injury 52

[DOI] [PMC free article] [PubMed] [Google Scholar] 354.Xiong, X

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AOD-9604 is administered via subcutaneous injection into fatty tissue, with the abdominal region being the preferred site