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Glutathione reductase (GR) can use NADPH to catalyze GSSG to produce GSH

doi:10.1038/nature22378 Zhao P, Liang YL, Belousoff MJ, et al

Along with this, cerebrovascular accident (CVA) is currently the second leading cause of death in the Western world, ranking after heart disease and before cancer[337], and experts predict that it is likely to be soon the most common cause of death worldwide[338]