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The level of oxidative stress, quantified by the oxidative stress markers, has been found elevated in aging individuals or people with bad lifestyles, taking unhealthy food, smoking, drinking alcohol, lack of physical exercise, and genetic predisposition

also reported that GRK2 expression is increased in blood lymphocytes of hypertensive patients and the impaired -AR-mediated vasorelaxation in the brachial artery is restored by treatment with heparin, a nonspecific GRK inhibitor [66]

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Effects of dietary selenium supplementation on intestinal barrier and immune responses associated with its modulation of gut microbiota

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