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Overall, the five different SH2 binding modes and mechanisms of pY competition that were observed so far may be one reason for the high selectivity of SH2-targeting monobodies

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Clearly, the structure and pathophysiological functions of apoE4 represent such a target

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Algammal College of Nursing, Qatar University, Doha, Qatar Fadwa Naji Alhalaiqa Department of Medical Rehabilitation (Physiotherapy), University of Maiduguri, Maiduguri, Nigeria Mohammed Usman Ali Nethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong, China Mohammed Usman Ali Department of Biological Sciences, National University of Medical Sciences (NUMS), Rawalpindi, Pakistan Liaqat Ali Center for Biotechnology and Microbiology, University of Swat, Swat, Pakistan Syed Shujait Ali Department of Pharmacy, Mohammed Al-Mana College for Medical Sciences, Dammam, Saudi Arabia Mohammad Daud Ali Institute of Health and Wellbeing, Federation University Australia, Melbourne, Victoria, Australia Sheikh Mohammad Alif School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia Sheikh Mohammad Alif, Mohammad Asghari-Jafarabadi & Yonas Getaye Tefera Department of Clinical and Community Pharmacy, An-Najah National University, Nablus, Palestine Samah W