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The British Dietetic Association recommends that vegans take a daily supplement of at least 10 g or a weekly supplement of 2,000 g to ensure adequate intake

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Overall, these findings suggest that ATXN3 aggregation may target directly or indirectly a metastable subproteome, thereby causing an increased susceptibility to multifactorial toxicity and, eventually, the collapse of many essential cellular functions, and this may help to explain the phenotypic complexities displayed in SCA3