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Rheinland-Verlag, Kln, pp 105112 Kreuz A, Schfer E (2002) A new archaeobotanical database programme

While an overdose of APAP yields peak serum concentrations (10 20 g/mL) within 4 hours, a patient taking the medication safely will achieve peak concentrations within 1.5 hours, with a half-life of 1.5 3 hours.8 APAP metabolism occurs within liver microsomes at the microscopic level

The low cytotoxicity of APE suggests that the extract exerts its protective effects without compromising cellular integrity, a critical consideration for potential pharmacological applications