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FCV Can cause a wide range of clinical signs depending on the strain, from mild upper respiratory signs and oral ulcers to a severe, life-threatening form that causes multiple organ failure

Role of ferroptosis and ferroptosis-targeting interventions in different types of AKI Although apoptosis has been identified as a form of tubular cell death in AKI for more than two decades, it is now considered that apoptosis is not the driving mechanism of AKI, as apoptosis interference appears to be clinically irrelevant in renal injury [108]

A Herxheimer reaction may occur during treatment, but more severe symptoms are not necessarily better

doi: 10.1016/j.berh.2016.04.003 136 PengYWuXZhangSDengCZhaoLWangMet al

10.1038/nm.4269 156 WrasidloW.TsigelnyI