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1936) Date: November 10, 2011 Event: Music Department Noonday Concert Location: Dickinson College Zoe Alice Doss Thrumston Clapping Music

Afrash H, et al

Morita M

Two years of adjuvant abemaciclib combined with endocrine therapy (ET) demonstrated a statistically significant and clinically meaningful overall survival (OS) improvement over ET alone, confirming the long-term benefit of CDK4/6 inhibition in the adjuvant setting

By analyzing the geometry, energetics, and prevalence of each interaction type, we highlight how structural information can guide rational lead optimization