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Increased type 2 innate lymphoid cells in patients with drug reaction with eosinophilia and systemic symptoms syndrome

The most intriguing and at the same time explanatory example comes from cancerous cells treated with ROS or with thiol-oxidizing agents

GSH-dependent protein de-nitrosylation occurs through a nitrosylation exchange mechanism that generates GSNO, which can be a substrate of the enzyme S-nitrosoglutathione reductase (GSNOR) that finally produces GSSG and ammonia (NH 3 ) [38,39,40]

10.1016/j.clinbiochem.2007.03.014PubMed Abstract | CrossRef Full Text | Google Scholar 7 ForoumadiA.RinehA.EmamiS.SiavoshiF.MassarratS.SafariF.et al (2008)