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Chan RC-F, Wang M, Li N, Yanagawa Y, Ono K, Lee JJ, Nel AE (2006) Pro-oxidative diesel exhaust particle chemicals inhibit LPS-induced dendritic cell responses involved in T-helper differentiation

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Th17 cells, whose proliferation is closely connected to gut dysbiosis, produce IL-17 A and GM-CSF, which not only activate microglia but also damage the BBB by acting on endothelial IL-17RA, resulting in a self-reinforcing permeability loop