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21 DialloI.SeveM.CuninV.MinassianF.PoissonJ

Similarly, one study showed that Tmed4(-/-) mice had endogenous regulatory T (Treg) cells that shifted toward a more inflammatory phenotype with enhanced anti-tumor activity in a colorectal cancer model (84)

In the lens, the majority of GSH was in the reduced form relative to the oxidised form

thus it seems highly likely that these processes occur in konzo, a motor neuron disease triggered in part by the consumption of toxic compounds that are well established to increase oxidative stress 43