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Description

Aging is commonly associated with gut dysbiosis, marked by reduced microbial diversity and a decline in beneficial bacterial populations, which has been linked to cognitive decline and increased frailty (Claesson et al., 2012

An indispensable substance for various physiological cellular functions, lactate plays a regulatory role in different aspects of energy metabolism and signal transduction

10.1016/j.jtemb.2019.126418 237 SkjrringeT.BurkhartA.JohnsenK

Resident gut microbiota play a dual role in maintaining host homeostasis and immune defense, serving as both essential partners in immune system evolution and potential contributors to AD development through dysbiosis