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In animal experiments, each larva was considered to be an independent biological replicate, and at least six animals were used per imaging modality (spinning-disc confocal and two-photon microscopy)

Prader-Willi syndrome: causes of death in an international series of 27 cases

FIGURE 3 FIGURE 4 FIGURE 5 It is known that NPM interacts with ARF in the nucleolus, and after DNA damage, both can translocate to the nucleoplasm and to cause disruption of p53-HDM2 interaction (Kurki et al., 2004b), which allow p53 stabilization and activation by, for example, phosphorylation in Ser15 (Loughery et al., 2014)

In Supplementary Tables S4 and S5 are reported the statistically significant differences obtained by comparing the levels of e-GST and e-CAT enzymatic activities in different species

The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity