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Similarly, the stem cell factor SOX2 directly binds and activates the SLC7A11 promoter to confer ferroptosis resistance in lung cancer stem cells, which can be abrogated by SOX2 oxidation at Cys265 [31]

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Decreased hepatic clearance of circulating immune complexes, generalized complement activation, and sharing of a specific epitope between human colonic and biliary epithelial cells have also been reported (Bodenheimer et al, 1983

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