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Description

Statements Author contributions XH: Data curation, Formal Analysis, Writing original draft

The recommended subcutaneous dose of 100250 mcg is extrapolated from both available research and anecdotal reports

Cumming WA, Thomas VJ

Retatrutide : Phase 2 completed for obesity (NEJM 2023, 338 patients) and Phase 2a for MASH

It provides a logical explanation for the development of dual targeting drugs such as MM-131 a bispecific anti-MET/EpCAM mAb [108] and also further drug discoveries targeting concurrently all three c-Met, EpCAm and Wnt pathway simultaneously to overcome both innate and acquired resistance to tyrosin kinase inhibitors (TKIs)