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Description

291,292 When cells accumulate large amounts of misfolded peptides and oxidatively damaged proteins, protein degradation systems are required to degrade them to maintain cellular homeostasis

10.1038/s41398-020-01135-3 148

M.O'NeillE.MunroJ.KnigI.AndersonK.KolchW.et al (2009)

These events induce proteotoxic stress, ultimately leading to cell death

Chromium and dermal toxicity A tragic example of unusually severe chromium intoxication has been reported from an electroplating factory where a young worker fell into a tank containing chromates, which has fatal consequences