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Enzyme-linked immunosorbent assay (ELISA) The concentration of PCSK6 in the cell culture supernatants were determined using a relevant PCSK6 ELISA kit (Innovative Research, Vancouver, Canada)

They work through very different biological pathways

doi: 10.1007/s11306-010-0254-3 28 TheodoridisGAGikaHGWantEJWilsonID

In addition to calcium overload, most PD-related genes, such as a-synuclein, PINK1, Parkin, LRRK2, DJ-1, GBA and ATPA13A2, are involved in mitochondrial function and autophagy-lysosome pathways, and mutations in these genes cause diverse alterations related to the progression of PD [12, 13]